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11 changes: 9 additions & 2 deletions .gitignore
Original file line number Diff line number Diff line change
Expand Up @@ -69,8 +69,13 @@ TCGA_BRCA_DATA/
!bioneuralnet/datasets/brca/
!bioneuralnet/datasets/brca/**/*.csv

!bioneuralnet/datasets/networks/
!bioneuralnet/datasets/networks/**/*.csv
!bioneuralnet/datasets/kipan/
!bioneuralnet/datasets/kipan/**/*.csv

!bioneuralnet/datasets/gbmlgg/
!bioneuralnet/datasets/gbmlgg/**/*.csv


feature_testing

# Sphinx documentation build
Expand Down Expand Up @@ -129,3 +134,5 @@ dpmon_cv_results_SAGE_FINAL
dpmon_tuning
GBMLGG
PAAN
dpmon_cv_results_GAT_FINAL
docs_notebooks
29 changes: 29 additions & 0 deletions CHANGELOG.md
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Expand Up @@ -118,3 +118,32 @@ and this project adheres to [Semantic Versioning](https://semver.org/).
## [1.1.3] - 2025-11-01

- **Tag update to Sync Zenodo and PIPY**

## [1.1.4] - 2025-11-08

### **Added**
- **New Utility Functions and Global Seed**

- **Imputation**:
- `impute_omics`: Imputes missing values (NaNs) using `mean`, `median`, or `zero` strategies.

- `impute_omics_knn`: Implements **K-Nearest Neighbors (KNN)** imputation for missing values in omics data.

- **Normalization/Scaling**:
- `normalize_omics`: Scales feature data using `Z-score`, `MinMax` scaling, or `Log2` transformation.

- **Methylation Data Transformation**:
- `beta_to_m`: Converts methylation `Beta-values to M-values` (log2 transformation).

- **Reproducibility Utility**:
- `set_seed`: Sets global random seeds across Python, NumPy, and PyTorch, including configuration for deterministic CUDA operations to ensure maximum experimental reproducibility.

- **New TCGA Datasets**

- **TCGA-KIPAN**: Added the Pan-Kidney cohort (KIRC, KIRP, KICH) to **DatasetLoader**.

- **TCGA-GBMLGG**: Added the combined Glioblastoma Multiforme and Lower-Grade Glioma cohort to **DatasetLoader**.

### **Changed**

- **Documentation Update**: Updated the online documentation (Read the Docs/API Reference) to include the new TCGA datasets and their respective classification results using the **DPMON**.
8 changes: 2 additions & 6 deletions MANIFEST.in
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Expand Up @@ -14,12 +14,8 @@ recursive-include bioneuralnet/utils *.R *.r
recursive-include bioneuralnet/datasets/monet *.csv
recursive-include bioneuralnet/datasets/example1 *.csv
recursive-include bioneuralnet/datasets/brca *.csv

# include bioneuralnet/datasets/brca/clinical.csv
# include bioneuralnet/datasets/brca/pam50.csv
# include bioneuralnet/datasets/brca/mirna.csv
# exclude bioneuralnet/datasets/brca/meth_*.csv
# exclude bioneuralnet/datasets/brca/rna_*.csv
recursive-include bioneuralnet/datasets/gbmlgg *.csv
recursive-include bioneuralnet/datasets/kipan *.csv

# Include documentation source files
prune docs
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2 changes: 1 addition & 1 deletion README.md
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Expand Up @@ -8,7 +8,7 @@
[![Documentation](https://img.shields.io/badge/docs-read%20the%20docs-blue.svg)](https://bioneuralnet.readthedocs.io/en/latest/)
[![DOI](https://zenodo.org/badge/DOI/10.5281/zenodo.17503083.svg)](https://doi.org/10.5281/zenodo.17503083)

## Welcome to BioNeuralNet 1.1.3
## Welcome to BioNeuralNet 1.1.4

![BioNeuralNet Logo](assets/LOGO_WB.png)

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